Zika virus: WHO declares global public health emergency, says causal link to brain defects ‘strongly suspected’

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Zika virus: WHO declares global public health emergency, says causal link to brain defects ‘strongly suspected’

The World Health Organization designated the Zika virus and its suspected complications in newborns as a public health emergency of international concern Monday. The action, which the international body has taken only three times before, paves the way for the mobilization of more funding and manpower to fight the mosquito-born pathogen spreading "explosively" through the Americas.
Zika, first identified more than 50 years ago, has alarmed public health officials in recent months because of its possible association with thousands of suspected cases of brain damage in babies. The WHO has estimated that the virus will reach most of the hemisphere and infect up to 4 million people by year's end.
WHO Director-General Margaret Chan said at a media briefing Monday that the primary reason for the designation was the "strongly suspected" causal relationship between Zika and the rare congenital condition called microcephaly. Even before that association is scientifically confirmed or disproved, members of an 18-member advisory panel said the seriousness of the cases being reported required action. Chan concurred, saying the consequences of waiting were too great.
“Even the clusters of microcephaly alone are enough to declare a public health emergency because of its heavy burden" on women, families  and the community, Chan said.
In addition, she noted, there is significant concern given the lack of vaccines and rapid, reliable diagnostic tests, as well as the absence of any viral immunity in the population since the Americas are being affected for the first time. A potential link to Zika is also suspected in adults who have been diagnosed with Guillain-Barré syndrome, a rare condition that can cause paralysis.
According to the latest figures on the epicenter of the outbreak, Brazil has 4,000 suspected cases of microcephaly, with 270 confirmed with evidence of an infection.
The WHO declaration represents its highest level of alert and is only invoked in response to the most dire threats. The first time was in 2009 during the H1N1 influenza epidemic that is believed to have infected up to 200 million worldwide; the second in May 2014 when a paralyzing form of polio re-emerged in Pakistan and Syria; and the third in August 2014 with Ebola in West Africa.
Identifying a global public health emergency now allows the WHO to help coordinate surveillance efforts, such as recording and monitoring cases of Zika, microcephaly and other neurological complications. Officials said countries need to standardize their surveillance for microcephaly, in which an abnormally small head signals incomplete brain development.
Zika’s emergence as a major concern has taken infectious disease experts by surprise. The virus has been popping up in various parts of the world for decades, but individuals have typically only suffered mild symptoms such as a rash or body aches. Nearly all those infected in the past recovered fully, though there were rare cases of complications.
In recent months, however, as reports about brain-damaged newborns began increasing, health officials have worried about Zika's impact on fetal development and have focused on trying to protect pregnant women from the virus. In January, the U.S. Centers for Disease Control and Prevention issued a travel advisory urging pregnant women to avoid travel to areas where the virus is actively spreading. That advisory has been expanded repeatedly and now lists more than two dozen countries and territories in Central America, South America and the Caribbean.
The WHO said Monday there is no reason for travel or trade restrictions at this time. Instead, health officials there reiterated their advice to pregnant women to wear appropriate clothing, use insect repellent and take other practical measures, such as sleeping under a bed net to avoid being bitten.
Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said the WHO’s declaration is the "official global sounding bell that governments and others need to start really paying attention to this."
Infectious disease experts and others have pressured the WHO to escalate its response to Zika for several months, warning of the mistakes world leaders made during the Ebola crisis when a lack of coordination delayed quarantines and treatment. Chan seemed to reflect their calls when she asked rhetorically during Monday's media briefing, "Can you imagine if we do not do all these works now and wait until the science comes out, then people will say, 'Why don't you take action?'"


Bruce Aylward, the WHO's director of outbreaks and health emergencies, said that the evidence pointing to both a “temporal and geographic association” between Zika and microcephaly was strong.
"This is definitely the right measure to be taking at this time based on the information available," he said.
Some public health experts said the WHO did not go far enough.
Lawrence Gostin, a public health and law expert at Georgetown University, said it was a mistake that WHO did not issue a travel alert for pregnant women visiting Zika-affected countries. The organization's failure to do so puts it at odds with the CDC's travel warning to pregnant women.
The countries affected typically have younger populations, which means more women of childbearing age who will be worrying about the virus and its potential harm. Some of these countries have had among the world’s higher birth rates recently.
From 2011-2015, according to data from the World Bank, Guatemala had 27 births per 1,000 people; Haiti, 25; and Bolivia, 24. The rate in Brazil – South America’s most populous country by far – was 15 births per 1,000 people during that same period.
Gostin said parents concerned for the welfare of their daughters should advise them to avoid going to affected areas if they are pregnant. "If this wave of Zika infections is followed by a wave of birth defects in nine months, it would be unconscionable," he said in a statement.
Some countries are asking women to indefinitely delay pregnancy. But most Latin American countries also restrict access to contraception and abortion, and that puts a heavy and unfair burden on young and often poor women, he said.
Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine in Texas, sees most countries in the Americas as ill-equipped to preemptively fight the disease. It already has moved rapidly from South America north into Mexico.
“What do you do that’s meaningful to prevent microcephaly?” Hotez asked. “It’s going to go beyond the current health budget of these countries. You’re going to have to get the buy-in of the presidents of these nations.”
Zika may even be harder to defeat than Ebola, according to Hotez. While that virus was more deadly and could spread from human to human, it was easier to contain by isolating infected patients and ensuring safe burials. Ebola affected roughly 30,000 people in four West African countries.  Zika could affect millions of people throughout the entire Western Hemisphere.
“This is more challenging and more complicated because of the vector and what you’re up against,” Hotez noted.
In an interview with the Reuters news agency, Brazilian Heath Minister Marcelo Castro said the outbreak is his country is worse than previously believed because an estimated 80 percent of people who become infected with the virus do not exhibit known symptoms.
Castro also said every municipality in Brazil will be required to report all Zika cases to a central database starting next week. In further controls, Brazil will join other nations in banning blood donations from people who had the virus.
Castro warned last week that Brazil was “badly losing” the battle against the mosquito blamed for spreading Zika and said that more than 220,000 members of Brazil’s military would be mobilized in eradication efforts. The plans included distributing mosquito repellent to about 400,000 pregnant women, according to Brazil’s O Globo newspaper.

 

Dede Koswara atau biasa dikenal dengan sebutan Dede Manusia Akar mengembuskan nafas terakhirnya

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BANGKAPOS.COM, BANDUNG - Dede Koswara atau biasa dikenal dengan sebutan Dede Manusia Akar mengembuskan nafas terakhirnya di ruang isolasi Rumah Sakit Umum Pemerintah (RSUP) Hasan Sadikin atau RSHS, Bandung, Sabtu (30/1/2016).
Banyak kisah yang dapat dipetik dari pria berpenyakit langka itu.
Belum ada keterangan resmi dari pihak RSHS terkait kematian lelaki asal Kecamatan Cihampelas, Kabupaten Bandung tersebut. Dede sebelumnya dikenal sebagai manusia akar karena menderita penyakit langka sehingga tubuhnya dipenuhi kutil.
Awalnya pihak RSHS melalui Kepala Sub Humas dan Protokoler RSHS dr Nurul Wulanshani, membenarkan meninggalnya lelaki yang menderita epidermodisplasia veruciformis atau giant cutaneous horn yang disebabkan human papiloma virus. "Benar, Almarhum meninggal pukul 03.30," katanya melalui pesan singkat.

Namun ternyata bukan penyakit tersebut yang menyebabkan meninggalnya pria yang disebut sebagai manusia akar ini.
Anggota tim infeksi RSHS Bandung, dr Rudi Wisaksana,spPD, mengatakan, Dede meninggal bukan karena penyakit giant cutaneous horn atau kutil meradang yang selama ini dideritanya. Dede meninggal akibat penyakit multi organ.
"Beliau meninggal karena gangguan multi organ, meliputi ginjal, paru-paru, hati dan otak. Kondisinya mengalami perburukan," ujar Rudi kepada wartawan di RSHS, Sabtu siang.
Rudi mengatakan, kutil yang ada di tubuh Dede semakin banyak, namun kerusakan multi organ Dede seperti ginjal, hati,paru-paru dan otak juga semakin buruk.
"Gangguan hati sudah diketahui sejak pertama kali penanganan tahun 2007. Tapi tidak berat. Sekarang ini kondisi hatinya semakin memburuk," katanya.
Selain itu, ujarnya, kondisi daya tahan tubuh Dede pun belakangan ini menurun. Sehingga, tubuhnya mudah terinfeksi virus.
Dede merupakan pasien RSHS yang memiliki penyakit kelainan kulit yang langka atau disebut dengan istilah giant cutaneous horn. Sejak 2007, pasien telah menjalani operasi sekitar 14 kali.

Operasi pengambilan jaringan kulit terakhir tanggal 16 Desember 2014 dan pulang tanggal 22 Desember 2014. Meski telah menjalani belasan operasi, dede tetap menjalani hidupnya dengan tabah.
Kisah kegigihan Dede berjuang melawan penyakitnya sempat menginspirasi banyak orang saat operasi pengangkatan kutilnya berhasil di tahun 2010.
Tim dokter yang mengoperasi Dede berhasil mengangkat 2,1 kilogram kutil dari kedua tangan pria yang dijuluki si "manusia akar" itu dalam operasi kesembilan.
"Total kutil yang diangkat itu mencapai 2,4 kg. Dari tangan kanan kami berhasil mengangkat 1,4 kg dan tangan kiri 0,7 kg," kata Ketua Tim Operasi Dr Hardisiswoe Soedjana di Rumah Sakit Hasan Sadikin (RSHS) Bandung, kala itu.
Ia menjelaskan, secara keseluruhan tim operasi tidak menemukan kendala dalam operasi kali itu. "Kami tidak menemukan kendala yang cukup berarti karena kami telah mengetahui keadaan Dede pada operasi sebelumnya," ujar Dr Hardisiwoe.

Proses operasi tersebut, kata Dr Hardisiswoe, berjalan sekitar tiga jam. "Operasinya berlangsung tiga jam. Jam 08.00 pagi masuk ruang operasi jam 11.00 selesai," katanya.

Siap-siap Games 'COC' Bakal Ditutup 29 Februari

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Siap-siap Games 'COC' Bakal Ditutup 29 Februari

TERSIAR kabar, game Coc (clash of clans) rencananya akan ditutup oleh pengembangnya pada 29 Februari 2016 mendatang.
Kabar akan ditutupnya games Coc ini tentunya membuat para penggemar Coc yang laris di android dan IOS ini merupakan bencana besar.
Hal tersebut dikarenakan para pengguna games Coc telah menghabiskan banyak uang demi bermain games tersebut. Banyak pemain yang khawatir bila games Coc benar-benar ditutup.

Mengenai adanya kabar Coc bakal ditutup pada 29 Februari mendatang diperkuat dengan upadate Coc yang dirilis supercell beberapa hari lalu.
Adanya informasi tersebut juga membuat para penggemar Coc mengeluhkan kalau mereka tidak dapat melakukan update CoC dengan notifikasi, jika perangkat yang digunakan tidak kompatibel.
Sejauh manakah kebenaran info tersebut?
Menurut salah satu sumber game baru Supercell yang bertajuk Clash Royale menjadi kambing hitam mengapa CoC akan ditutup.
Lalu apakah Supercell benar-benar akan menutup server CoC?
Kabar ini tersebar pertama kali lewat forum Supercell dengan nama Anoushka.
Dia mengatakan bahwa, "Clash of Clans akan tutup pada 29 Februari 2016. Atas nama tim pengembang, kita ingin berterima kasih untuk dukungan selama ini. Bagi players yang masih memiliki banyak sekali gems, lebih baik segera menghabiskan gems tersebut sebelum akhirnya server ditutup".Namun tidak lama setelah berita ini tersebar, salah satu staf Supercell membantah bahwa CoC akan ditutup, kemudian dia mangatakan “apa kira kira yang Anda alakukan jika benar-benar coc ditutup pada Februari mendatang?